The game was close the entire time, but with seconds left in regulation, St. Catherine's nailed two free throw shots to seal the win and claim their 3rd state title.
It was the second consecutive Division 3 title for the Angels, who also won the Division 2 title in 2005.
St. Catherine's forward James Haarsma led all scorers with 24 points.
Blugold Scott Christopherson led Aquinas with 18 points.
La Crosse finishes the season at 26-1