Santana is 11-and-6. He allowed four hits to win his fifth straight start. He is a staggering 41-and-4 with a Major League-leading 427 strikeouts in games played after the All-Star break since 2003.
The left-hander didn't allow a runner past first base all night.
Luis Castillo added two hits and two R-B-Is for the Twins, who handed the A's their sixth loss in seven games.
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