CLEVELAND (AP) -- Giannis Antetokounmpo matched his career high with 44 points and the Milwaukee Bucks beat the Cleveland Cavaliers 114-102 on Friday night despite missing two starters.
Antetokounmpo's big night came after being held to a season-low 12 points Wednesday night in a loss to Indiana. He was 14 of 19 from the field, made 16 of 21 foul shots, and had 14 rebounds and eight assists.
Khris Middleton, the Bucks' second leading scorer, was out with a sprained right finger. Malcolm Brogdon, fourth on the team in scoring, didn't play because of a sore left hamstring.
The Bucks never trailed and held off a late Cleveland spurt. The Cavaliers cut the lead to five midway through the fourth quarter on Cedi Osman's 3-pointer, but Antetokounmpo had a three-point play and an assist on Brook Lopez's basket that beat the shot clock, pushing the lead to 111-99.
Not only was Antetokounmpo coming off a subpar game, Wednesday's 113-97 loss was their largest margin of the season.
Brook Lopez scored 19 points and Eric Bledsoe had 16 for the Bucks, who have the second-best record in the Eastern Conference.
Jordan Clarkson scored 23 points, and Larry Nance Jr. had 14 for Cleveland. Rookie point guard Collin Sexton had five points after scoring in double figures in 18 straight games.
Antetokounmpo made an instant impression after Milwaukee won the opening tip when he dunked on Osman on a set play in the halfcourt offense. He ended the half by finding Pat Connaughton for a 3-pointer.
Cavaliers guard Matthew Dellavedova dove into the scorers table saving a ball that was headed out of bounds in the second quarter and crashed into Fred McLeod, the team's television play-by-play man.
The collision sent both to the floor while papers and notes went flying. Dellavedova climbed over the table and returned to action. McLeod was helped up and continued to call the game, but his chair got the worst of the impact and was replaced.
Cleveland acquired Dellavedova from Milwaukee for George Hill last week. Dellavedova scored 10 points while Hill two.
The Bucks are in a stretch of one game in four days, giving coach Mike Budenholzer a chance to rest players who are dealing with minor injuries.
Middleton is averaging 17.4 points, but has been a major slump, hitting 16 of 47 from the field in the last four games while dealing with the finger issue.
Brogdon is averaging 15.3 points and is shooting 52 percent from the field. He's made 47 percent of his 3-point attempts.
Milwaukee was off Thursday and doesn't play again until Monday. Connaughton and Tony Snell started against Cleveland.
Bucks: Milwaukee is 9-0 after a loss. .... Antetokounmpo sat out with a sore neck Monday in a 108-92 win over the Cavaliers. ... Milwaukee broke a six-game losing streak in Cleveland.
Cavaliers: Cleveland's starters had no assists in the first half. .... C Channing Frye was given a flagrant foul on Antetokounmpo under the basket in the third quarter. ... Cleveland came in looking for its first three-game winning streak of the season.
Bucks: At Detroit on Monday night.
Cavaliers: Host Philadelphia on Sunday.